======Simulating an Epidemic with GloGerm====== **Materials: **{{$demo.materials_description}}\\ **Difficulty: **{{$demo.difficulty_description}}\\ **Safety: **{{$demo.safety_description}}\\ \\ **Categories:** {{$demo.categories}} \\ **Alternative titles:** Tracing Patient Zero Activity ====Summary==== {{$demo.summary}} ====Procedure==== - Prepare one petri dish per student containing gauze soaked with mineral oil and cornstarch. Replace cornstarch with GloGerm in one dish to designate patient zero. - Give each student a latex glove, instructing them to put it on their non-writing hand. - Students rub the gauze from their dish onto the glove. Only one student unknowingly has the GloGerm “infection.” - Conduct three to five rounds of controlled handshakes. Ensure students record who they shake hands with each round. - After the last round, test for infection by examining gloves under UV light in a controlled testing station. - Record which students are infected and reconstruct the path of transmission back to patient zero. - Discuss the spread, highlighting how quickly an epidemic can expand and the exponential growth of infections. ====Links==== 📄 The Epidemic: a Large Group Activity That Demonstrates Transmission of Infectious Agents - American Society for Microbiology: [[https://asm.org/lesson-plans/the-epidemic-a-large-group-activity-that-demonstr]]\\ ====Variations==== * Test a few students midway through the activity to simulate real-world diagnostic testing. * Increase or decrease the number of handshake rounds to change infection rates. * Have multiple “patient zeros” to simulate overlapping outbreaks. * Compare different handshake intensities (light vs. vigorous) to observe spread differences. ====Safety Precautions==== * Ensure students wear gloves to avoid direct contact with GloGerm and oils. * Use safety glasses when handling UV lights. * Dim the lights or use a cardboard isolation box for safe UV visualization. * Remind students to use standard handshakes only, not to intentionally spread oil over large glove areas. * Test gloves before the activity to check for any fluorescent specks that may cause false positives. ====Questions to Consider==== * What does this activity reveal about how quickly infections can spread? (Infections spread exponentially with repeated contacts.) * How can false positives or false negatives affect our understanding of an epidemic? (They may hide true infections or falsely label healthy individuals as infected.) * Why is recording encounters important for identifying patient zero? (It provides a traceable network of contacts.) * How is this simulation similar to and different from real epidemics? (It shows contact-based spread but simplifies real-world complexities such as immunity, symptoms, and incubation periods.) * How do preventive measures in real life (e.g., vaccination, masks, handwashing) compare to the “glove” or control measures in this activity?