======Sheep Brain Dissection====== **Materials: **{{$demo.materials_description}}\\ **Difficulty: **{{$demo.difficulty_description}}\\ **Safety: **{{$demo.safety_description}}\\ \\ **Categories:** {{$demo.categories}} \\ **Alternative titles:** ====Summary==== {{$demo.summary}} ====Procedure==== *Follow instructions provided in the links below. ====Links==== Sheep Brain Dissection - Center for Science Education - Great Diseases: {{youtube>-fDWH4_5DhI?}}\\ Sheep brain dissection- Ren Hartung: {{youtube>vE3Yf_xy_mE?}}\\ 📄 Sheep Brain Dissection - LibreTexts: [https://bio.libretexts.org/Bookshelves/Human_Biology/Human_Anatomy_Lab/11%3A_The_Central_Nervous_System_(Brain)/11.07%3A_Sheep_Brain_Dissection]]\\ 📄 Lab: Sheep Brain Dissection - Elizabeth Moretz: [[https://elizabethmoretz.weebly.com/uploads/4/4/5/6/44567783/sheep_brain_dissection.pdf]]\\ 📄 Virtual Sheep Brain Dissection - The Biology Corner: [[https://www.biologycorner.com/2020/12/27/brain-dissect-virtual/ ====Variations==== *Compare a sheep brain to a human brain model or 3D digital atlas to highlight differences in proportion and orientation. *Prepare thin sagittal or coronal sections (under instructor supervision) to visualize ventricles and deeper nuclei. *Relate external skull features to brain orientation by discussing foramen magnum position in quadrupeds versus bipeds. *Integrate a functional mapping exercise that links identified structures to sensory, motor, or integrative roles. ====Safety Precautions==== *Wear gloves and a lab coat; tie back hair and avoid loose clothing. *Use scalpels and scissors with care; always cut on the tray with the specimen resting flat (never cut while holding the specimen). *Handle preserved tissues and fluids as potential chemical irritants; avoid skin and eye contact and work in a well-ventilated area. *Dispose of tissues as biological waste and blades in approved sharps containers; follow local protocols. *Sanitize the workspace and instruments after the lab; wash hands thoroughly. *Be mindful of latex sensitivity; provide nitrile gloves as needed. ====Questions to Consider==== *Why is the sheep cerebrum proportionally smaller than the human cerebrum? (Sheep rely more on midbrain and olfactory processing, whereas humans have expanded cortical areas for higher cognition.) *How does spinal cord orientation differ between sheep and humans, and what skull feature reflects this? (Sheep have a more horizontal cord and a posterior foramen magnum; humans have a vertical cord and a centrally located foramen magnum.) *What is the function of the corpus callosum observed in the midline cut? (It contains commissural fibers that connect the left and right cerebral hemispheres.) *What is the optic chiasma and why is it ventrally located? (It is where optic nerves partially cross; it lies near the base of the brain along the visual pathway.) *Why might the pituitary gland be missing after dura removal? (It is attached by a slender stalk and often tears away with the dura.) *What do gyri and sulci accomplish? (They increase cortical surface area, allowing more neurons within a limited skull volume.) *How do white matter and gray matter differ in appearance and function? (White matter is lighter due to myelinated axons for rapid signaling; gray matter contains neuron cell bodies for processing.) *Where are the superior and inferior colliculi located and what are their roles? (On the dorsal midbrain; superior colliculi coordinate visual reflexes and inferior colliculi process auditory reflexes.)