======Origami DNA Model====== **Materials: **{{$demo.materials_description}}\\ **Difficulty: **{{$demo.difficulty_description}}\\ **Safety: **{{$demo.safety_description}}\\ \\ **Categories:** {{$demo.categories}} \\ **Alternative titles:** Paper DNA Model, Folding a DNA Double Helix ====Summary==== {{$demo.summary}} ====Procedure==== - Print out the origami DNA templates (colored or blank) from the text link below. - Fold according to the instructions and video to form a double helix of DNA. ====Links==== DNA origami: how to fold a double helix - yourgenome: {{youtube>0jOapfqVZlo?}}\\ 📄 Origami DNA (Coloured model) - yg: [[https://www.yourgenome.org/theme/origami-dna/]]\\ \\ Building the Paper Model of DNA - RCSBProteinDataBank: {{youtube>EweN-gW2bEM?}}\\ 📄 DNA Paper Model (similar, but has molecular model printed on) - PDB 101: [[https://pdb101.rcsb.org/learn/paper-models/dna]]\\ ====Variations==== * Use the blank template for students to practice DNA base-pairing before folding. * Create longer DNA models by printing and connecting multiple templates. * Write a short genetic code (a sequence of bases) along the folded DNA to represent real genes. ====Safety Precautions==== * Use scissors carefully when cutting out templates. * Ensure younger students have supervision during cutting and folding. * Keep paper scraps tidy to avoid clutter or slipping hazards. ====Questions to Consider==== * What do the “rungs” of the DNA origami ladder represent? (Base pairs between adenine-thymine and cytosine-guanine.) * Why is the DNA structure described as a double helix? (Because two strands twist around each other like a spiral staircase.) * How does this paper model help us visualize DNA more easily than looking at chemical diagrams? (It makes the 3D shape tangible and easier to understand.) * What role do complementary base-pairing rules play in DNA replication? (They ensure that DNA copies are accurate, with each strand serving as a template for the other.)